Pre-eclampsia Prophylaxis – Questions

The following should be answered after reading

Pre-clampsia Prophylaxis



  1. What should women who are at high risk of developing pre-eclampsia be given in pregnancy?











1A. Aspirin 75mg OD

2. When should they start this medication?










2A. From 12 weeks until the birth.

3. What are 4 conditions which would make a woman high risk of pre-eclampsia?











1.  Hypertensive disease during previous pregnancies,

2. Chronic Kidney disease,

3. Autoimmune disorders such as SLE or antiphospholipid syndrome.

4. Diabetes (type 1 or 2)



4. There are two ways in which hypertension in pregnancy can be diagnosed what is the first?










4A. A systolic BP over 140 or a diastolic over 90

5. What is the second way in which hypertension in pregnancy can be diagnosed?









5A. An increase above the booking reading – raise in 30mmHg systolic or a raise in 15mmHg of diastolic.










6. What are the three categories hypertension in pregnancy can be categorised into?










6A. Pre-existing hypertension,

Pregnancy-induced (or gestational) hypertension,


7. In pre-existing hypertension, describe:

The blood pressure and week of gestation











In pre-existing hypertension, the BP is above 140/90 before 20 weeks of pregnancy.


7.2Q: In pre-existing hypertension, describe the urine and fluid status.









7.2Q: In pre-existing hypertension there is no proteinuria and there is no oedema.


8Q. In pre-existing hypertension, describe:

What proportion of pregnancies does it happen in?










8APre-existing hypertension is present in 3-5% of pregnancies.


9Q. In which patients is pre-existing hypertension more common in?











9A: Pre-existing hypertension is more common in older women.


10 Q: What is the definition of hypertension in pergnancy-induced hypertension?












10A: BP>140/90 occurring in second half of pregnancy (after 20 weeks)


11Q: In pregnancy-induced hypertension, describe the urine and fluid status.











11A. In pregnancy induced  hypertension there is no proteinuria and no oedema

9.In pregnancy-induced hypertension, describe:

What percentage of pregnancies suffer?










Around 5-7% of pregnancies.


10. In pregnancy-induced hypertension, describe:

What is the natural history for the blood pressure?










10A. The hypertension resolves following birth – typically after a month.


11Q. If a woman suffers from pregnancy-induced hypertension what will she pre-disposed to?












11A. Women with PIH are at an increased risk of future pre-eclampsia or hypertension later in life.

12Q: What is pre-eclampsia?












12A: Pre-eclampsia is Pregnancy induced hypertension associated with Proteinuria.











13Q: Does Oedema occur in pre-eclaspisa?











13A: Oedema may occur in pre-eclampsia but is less commonly used as a criteria.


14Q: What proportion of pregnancies are effected by pre-eclampsia?











14A: Pre-eclampsia effects about 5% of pregnancies.