Nephrotic syndrome is a triad of:
- Massive Proteinuria ( >1g/m2 per 24ours )
- Hypoalbuminaemia ( <25g/l )
- hypercoagulability (due to loss of antithrombin III),
- predisposition to infection.
Peak incidence: 2-5years of age
Around 80% are due to minimal change glomerulonephritis
90% respond to high dose oral steroids and have good prognosis