Lewis Body Dementia
- Shares characteristics of Parkinson’s and dementia
- Usually sleep more than two hours in the day
- Visual hallucinations
- Parkinsonian movements
- Delusions more common than other types of dementia
- Syncopal attacks are more common than other types
- Don’t prescribe antipsychotics – they can make movements worse and result in sudden death
What are Lewy Bodies?
- Abnormal aggregations of a protein alpha-synuclein.
- When these develop int he cortex they result in dementia.
- Alpha-synuclien are also present in brains of Parkinson’s patients but they appear in a different pattern to Lewy Bodies
- Memory loss and thinking problems similar to Alzheimer’s
- BUT: more likely to have:
- Sleep disturbances
- well-formed visual hallucinations
- slowness / gait imbalance / other parkinsonian movement features