Leukaemia – Questions

What is the most common malignancy in childhood?

 

 

 

 

 

 

 

 

 

 

Acute Lymphoblastic Leukaemia

 

2. Of the childhood leukaemias, what proportion is ALL?

 

 

 

 

 

 

 

 

 

 

2A: ALL accounts for 80 of childhood leukaemias

3: What is the peak age group for ALL?

 

 

 

 

 

 

 

 

 

 

3A: peak age is between 2 and  5 years

 

4. Is ALL seen equally in boys and girls?

 

 

 

 

 

 

 

 

 

 

4A: ALL is slightly more common in boys

 

5: What are the clinical features of ALL divided into?

 

 

 

 

 

 

 

 

 

 

5A: ALL’s clinical features can be divided into those resulting from bone marrow failure and Other features.

 

6: what are the clinical features resulting from bone marrow failure?

 

 

 

 

 

 

 

 

 

 

 

6A: The clinical features of ALL related to failure of the bone marrow are: Anaemia – lethargic/pallor, Neutropenia – Frequent/severe infections and thrombocytopenia – easy bruising/petechiae

7: what are the other features of ALL?

 

 

 

 

 

 

 

 

 

 

 

 

7A: Bone pain, Hepatomegaly, Splenomegaly, Testicular swelling

 

8; What are the types of all? (quick)

 

 

 

 

 

 

 

 

 

8A: 1. Common ALL, 2 T-cell ALL, 3. B-cell ALL

 

9: What are the relative percentages of the different types of ALL?

 

 

 

 

 

 

 

 

 

 

 

9A: Common is 75%, T-cell ALL is 20% (T for T-cell ad T for Twenty percent), B-cell 5%.

 

10: What are the poor prognostic factors for a kid presenting with Acute Lymphoblastic Leukaemia?

 

 

 

 

 

 

 

 

 

 

 

10A: Age less than 2 or more than 10, B or T cell surface antigen positive, Male, Non -caucasian