• In palliative care a laxative should be co-prescribed with opioids as constipation is so common
  • Use co-danthramer in this situation which is a combination of Daedalus softener and peristaltic stimulant
  • Methylnaltrexone bromide (sub cut injection) can be used in termina patients where other laxatives have failed
  • Prucalopride is licensed for women in whom two different laxatives snd lifestyle changes have failed to bring about relief.